Glucosamine is a type of nutrient known as an ‘amino sugar’. It is converted into larger molecules that go to make up connective tissue. Clinical trials and studies have shown that when taken as a dietary supplement, glucosamine combined with sulphate can help to prevent the breakdown of cartilage which occurs in osteoarthritis. Glucosamine sulphate is taken up by joint tissue, stimulates the production of glycoaminoglycans (the building blocks of cartilage), and can reduce joint pain, tenderness and swelling, allowing joint movement to increase. The supplement is often given with vitamin C and the amino acid tyrosine to optimize its action.