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Linda Lazarides'
Nutritional Health Bible
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Digestion

The process whereby food is broken down by digestive juices to enable nutrients to be absorbed into the blood and lymphatic system and used for energy, growth and repair.

The digestive process begins in the mouth, with chewing of the food and mixing with saliva, which contains the enzyme salivary amylase that begins the breakdown of starch. Once the food is swallowed and reaches the stomach, it is mixed with acid and pepsin, which begins the breakdown of protein in the food.

When food leaves the stomach it is in the form of a thick creamy liquid called chyme, and is very acidic. As chyme leaves the stomach and enters the duodenum (the first part of the small intestine) its acidity stimulates the liver and pancreas to release bicarbonate, which changes the pH of the chyme, making it alkaline. This alkalinity is necessary for the next stage of digestion, using enzymes secreted mainly by the pancreas but also by the small intestine itself. The pancreas contributes lipase for fat (lipid) digestion, amylase for starch digestion, and protease for protein digestion. Bile released by the gall bladder emulsifies fat particles, enabling pancreatic enzymes to work on them more easily.

Once digested, the nutrients from the food, including vitamins and minerals, are absorbed into the cells which line the small intestine. Finger-like projections called 'villi' increase the surface area of the small intestine approximately to the size of a tennis court, thus optimizing absorption. Fatty substances pass into the lymphatic system, only entering the bloodstream once they have travelled as far as the large veins in the neck. Other substances are absorbed into the blood and carried straight to the liver for processing, after which nutrients are distributed and taken up (assimilated) by the cells of the body's various tissues.

Substances which aid digestion

Produced by Name Action
The saliva glands
in the mouth
Salivary amylase, also known as ptyalin Begins to break down starch
The stomach
(gastric juice)
Gastrin Hormone stimulating the production of gastric juice
  Hydrochloric acid Kills microbes, solubilizes protein
  Pepsin Enzyme which begins protein breakdown
The liver and gall bladder Bicarbonate Neutralizes acid coming from the stomach
  Bile salts Emulsify fats
The pancreas Aminopeptidase and carboxypeptidase

Enzymes required for the final stages of protein digestion
Amylase Carbohydrate digesting enzyme
  Bicarbonate Neutralizes acid coming from the stomach
  Lipase Fat digesting enzyme
  Proteases (trypsin and chymotrypsin) Protein digesting enzymes
Small intestine Carboxypeptidase Enzyme required for final stages of protein digestion
  Cholecystokinin Hormone stimulating the gall bladder to release bile
  Disaccharidases (sucrase, lactase, maltase) Enzymes needed to split disaccharides to simple sugars (see Carbohydrates)
  Gastric-inhibitory peptide Hormone slowing the production of gastric juices and gastrointestinal motility
  Secretin Hormone stimulating the production of pancreatic juice

Adapted from the Nutritional Health Bible by Linda Lazarides
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