Of 179 patients with eczema, 111 showed improvement after several weeks'
supplementation with 8 capsules a day of evening primrose oil. Medications were
reduced in many cases. Stewart JCM et al: Treatment of severe and moderately
severe atopic dermatitis with evening primrose oil (Epogam): a multi-centre
study. J Nutr Med 2:9-15, 1991.
An analysis of nine controlled trials of evening primrose oil (Epogam)
against eczema found that Epogam was significantly more effective than placebo,
particularly against itching. Morse PF et al: Meta-analysis of
placebo-controlled studies of the efficacy of Epogam in the treatment of atopic
eczema. Relationship between plasma essential fatty acid changes and clinical
response. Br J Dermatol 121(1):75-90, 1989.
In a double-blind multicentre study on 145 eczema patients randomly assigned
to fish oil or corn oil supplements there was a 30% improvement in clinical
score in the fish oil group and a 24% improvement in the corn oil group. Soyland
E et al: Dietary supplementation with very long-chain n-3 fatty acids in
patients with atopic dermatitis. A double-blind multicentre study. Br J Dermatol
130(6):757-64, 1994.
In a double-blind study for 12 weeks, fish oil supplementation resulted in
improvements in scaling and itching. Bjorneboe A et al: Effect of dietary
supplementation with eicosapentaenoic acid in the treatment of atopic
dermatitis. Br J Dermatol 117(4):463-9, 1987.
