Tyrosine metabolism normalized in a group of glaucoma patients administered
the antioxidant lipoic acid in combination with cofactors pyridoxal phosphate,
vitamin C and iron, and the studied parameters improved. The authors conclude
that the literature supports the administration to glaucoma patients of lipoic
acid with vitamins B1, B2, B5, B6 (as P5P) and vitamin C. Filina AA et al:
Effect of lipoic acid on tyrosine metabolism in patients with open angle
glaucoma. Vestn Oftalmol 107(3):19-21, 1991.
Since magnesium is a natural calcium-channel blocker, 10 glaucoma patients
were given magnesium supplements twice daily. After 1 month the visual fields
tended to improve and all 3 measured blood flow parameters were significantly
improved. Gaspar AZ et al: The influence of magnesium on visual field and
peripheral vasospasm in glaucoma. Ophthalmologica 209(1):11-13, 1995.
45 glaucoma patients were given either the antioxidant lipoic acid or
placebo. Improvement of the biochemical parameters, visual function and of the
coefficient of efficacy of liquid discharge was better in 45-58% of the eyes
examined, the better results being in stage II glaucoma. Filina AA et al: Lipoic
acid as a means of metabolic therapy of open-angle glaucoma. Vestn Oftalmol
111(4):6-8, 1995.
35 patients with primary open-angle glaucoma were treated by hyperbaric
oxygenation combined with antioxidants for 5 years. Stabilization of the visual
function was obtained in 80% of patients but in only 35% of controls. Popova ZS
et al: Treatment of primary open-angle glaucoma by the method of combined use of
hyperbaric oxygenation combined with antioxidants. Vestn Oftalmol 112(1):4-6,
1996.
